Ever-increasing through circles: Long single-stranded DNA molecules with repetitive sequence units were synthesized on gold nanoparticles through rolling circle amplification (RCA, see scheme). These special DNA–AuNP conjugates were then used as a scaffold for assembling periodic 3D nanostructures, which may find applications in nanocomputing devices, nanoelectronic circuits, and ultrasensitive biosensors.
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Zhao et al. (2006) studied this question.
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