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Single-case observational analysis reveals phenotypic markers supporting high-frequency neural drive in an older adult, suggesting bio-cybernetic control of mitochondrial function.
This paper introduces the Bio-Electrodynamic Human Firmware Model, a novel bio-cybernetic closed-loop framework for the postural, energetic, neuromuscular, and metabolic regulation of the human organism. Moving beyond fragmented physiological models, the core hypothesis proposes that the central nervous system employs a functionally significant High-Frequency Neural Drive (HFND) in the range of 400–1000 Hz, associated with the olivo-cerebellar control architecture. The model posits that this high-frequency organization establishes electrotonic synchrony and mechanical coherence across the muscle matrix, modulating mitochondrial function beyond classical biochemical pathways and driving a "Just-in-Time" endogenous recycling loop for tissue remodeling. Phenotypic and clinical biomarker data from long-term self-observation of a 63-year-old subject are presented as indirect empirical support. Seven falsifiable, experimentally testable predictions are defined to challenge the hypothesis through high-bandwidth neurophysiological and metabolic measurements.
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Dmytro Taran (2026) studied this question.