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September 4, 2026World Journal of Pharmaceutical ResearchOpen Access

Pharmacoeconomics Evaluation of Antibiotic Therapy in Hospitilized Patients

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Authors

MMM. Senthil Raja*, R. Dhanusri, K. Someshwaran, M. Ashoktharan, M. Madhanprasanth

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Overview

Observational study reveals high recovery rates alongside substantial treatment costs in hospitalized patients, highlighting the financial and clinical value of targeted antibiotic therapy.

Key Points

  • To evaluate the prescribing patterns, clinical outcomes, and direct healthcare costs associated with antibiotic therapy in hospitalized patients.
  • Conducted a three-month observational study examining clinical records and treatment expenses of hospitalized patients receiving antibiotic therapy (N=130).
  • Recorded demographic profiles, primary infection types, specific antibiotic selections, routes of administration, and treatment strategies (empirical versus targeted).
  • Clinical outcomes revealed that 82 (63.1%) patients achieved complete recovery, 45 (34.6%) improved, and 3 (2.3%) showed no clinical improvement.
  • Urinary tract infections were the most frequent diagnosis (11.54%), while ceftriaxone was the most common antibiotic (11.5%), with intravenous delivery utilized in 69.2% of patients and targeted therapy in 49.2%.
  • The mean total treatment cost was ₹15,592.30 per patient, with general hospital charges representing the largest expense component.

Cite This Study

M. Senthil Raja*, R. Dhanusri, K. Someshwaran, M. Ashoktharan, M. Madhanprasanth (2026) studied this question.

synapsesocial.com/papers/6a9a862b5d9e33f25c631ceehttps://doi.org/10.5281/zenodo.22252652
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