What question did this study set out to answer?

To examine whether muscle strength, physical function, lean mass, and muscle density independently influence the risk of hospitalization in community-dwelling older adults.

July 29, 2009Journal of Media Literacy EducationOpen Access

Do Muscle Mass, Muscle Density, Strength, and Physical Function Similarly Influence Risk of Hospitalization in Older Adults?

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Authors

PCPeggy M. CawthonSutter Health KFKathleen M. FoxAmgen (United States)SGShravanthi R. GandraMerck & Co., Inc., Rahway, NJ, USA (United States)

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Implication

Prospective cohort study finds low muscle density and poor physical strength predict increased hospitalization in older adults, highlighting muscle quality over size.

Key Points

To examine whether muscle strength, physical function, lean mass, and muscle density independently influence the risk of hospitalization in community-dwelling older adults.
Prospective cohort study analyzing 3,011 adults aged 70 to 80 years from two U.S. clinical centers participating in the Health, Aging and Body Composition Study.
Assessed grip and knee extension strength, lean mass, walking speed, chair stand pace, and thigh computed tomography scans for muscle area and density across an average follow-up of 4.7 years.
Calculated incident rate ratios (IRRs) of hospitalization for race- and sex-specific quartiles using multivariable negative binomial regression models adjusting for age, BMI, health status, and comorbidities.
During follow-up, 1,678 participants (55.7%) experienced one or more hospitalizations.
Participants in the lowest quartile of muscle density faced a significantly higher hospitalization rate (multivariate IRR = 1.47, 95% CI: 1.24–1.73) compared with the highest quartile.
Weakest grip strength similarly increased hospitalization risk (multivariate IRR = 1.52, 95% CI: 1.30–1.78, Q1 vs. Q4), alongside poor knee strength and slower functional pace, whereas lean mass and muscle area showed no association.

Cite This Study

Cawthon et al. (2009) studied this question.

synapsesocial.com/papers/6a9a895c1c51d4e2d58de160 https://doi.org/10.1111/j.1532-5415.2009.02366.x

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Implication

Prospective cohort study finds low muscle density and poor physical strength predict increased hospitalization in older adults, highlighting muscle quality over size.

Do Muscle Mass, Muscle Density, Strength, and Physical Function Similarly Influence Risk of Hospitalization in Older Adults?

Discussion

Member takes

Implication

Key Points

Cite This Study

Do Muscle Mass, Muscle Density, Strength, and Physical Function Similarly Influence Risk of Hospitalization in Older Adults?

Discussion

Member takes

Implication

Key Points

Cite This Study

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