Key result
Emergency mitral valve repair for papillary muscle rupture resulted in an 8-year overall survival of 94.4%, comparable to 86.5% for elective ischemic mitral regurgitation repair (p=0.730).
Why the study?
Emergency or urgent surgery is often required for papillary muscle rupture and active mitral valve infective endocarditis, motivating an analysis of outcomes after emergency or urgent mitral valve repair.
Does emergency or urgent mitral valve repair yield satisfactory outcomes compared to elective repair in patients with papillary muscle rupture or active infective endocarditis?
Cohort (n=195)
No
Does emergency or urgent mitral valve repair yield satisfactory outcomes compared to elective repair in patients with papillary muscle rupture or active infective endocarditis?
Answers are grounded in this paper and cite their sources.
Emergency or urgent mitral valve repair for papillary muscle rupture or active infective endocarditis is feasible and yields early and mid-term survival comparable to elective operations.
Background Emergency or urgent surgery is often required in patients with papillary muscle rupture and active mitral valve infective endocarditis. The aim of this study was to analyze the outcomes of patients with active endocarditis who underwent emergency or urgent mitral valve repair. Methods From 2005 to 2014, 154 ischemic mitral regurgitation patients and 41 infective endocarditis patients underwent mitral valve repair in our institution; 23 had emergency operations due to papillary muscle rupture, and 18 with active infective endocarditis underwent urgent surgery. Results Cardiopulmonary bypass time (141.4 ± 43.3 versus 145.3 ± 46.5 min) and crossclamp time (77.7 ± 34.1 versus 79.2 ± 33.0 min) were similar in the papillary muscle rupture and elective ischemic mitral regurgitation subgroups, and major postoperative complications were comparable. Hospital mortality was 17.4% in the papillary muscle rupture subgroup and 8.4% in the elective ischemic mitral regurgitation subgroup. Cardiopulmonary bypass time (103.6 ± 37.0 versus 75.5 ± 20.8 min) and crossclamp time (61.7 ± 21.2 versus 45.3 ± 18.0 min) were significantly longer in infective endocarditis patients. There were no major complications or hospital deaths. Eight years postoperatively, overall survival was 94.4% and 86.5% in the papillary muscle rupture and elective ischemic mitral regurgitation subgroups, respectively ( p = 0.730). Overall survival was 100% in both infective endocarditis subgroups. Conclusion The feasibility and effectiveness of emergency or urgent mitral valve repair in patients with papillary muscle rupture and active infective endocarditis are satisfactory. Early and mid-term outcomes are comparable to those of elective operations.
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Li et al. (2020) conducted a cohort in Papillary muscle rupture and active infective endocarditis (n=195). Emergency or urgent mitral valve repair vs. Elective mitral valve repair was evaluated on Overall survival at 8 years (p=0.730). Emergency mitral valve repair for papillary muscle rupture resulted in an 8-year overall survival of 94.4%, comparable to 86.5% for elective ischemic mitral regurgitation repair (p=0.730).
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