Comparative Anti-Anaemia Efficacy of atropha tanjorensis and Telfairia occidentalis Leaf Extracts in Aluminium Chloride (AlCl₃) Induced Anaemia in Albino Rats

Anaemia is a blood illness that threatens public health. The anti-anaemia property of Jatropha tanjorensis and Telfairia occidentalis is known. However, information on their respective measures of anti-anaemia potential is veiled. Comparing the anti-anaemia potential of extracts from the said plants is pivoted in this investigation. J. tanjorensis (JTLE) and T. occidentalis (TOLE) leaves were ground into a fine powder and then macerated. Twenty-one (21) mature male albino rats were divided into seven groups of three (3) rats per group. Anaemia was induced in groups II-VII, after which extracts were administered orally for 21 consecutive days. Group I (normal control) and Group II were not administered extract. The third and fourth groups received 200 mg/kg of T. occidentalis and J. tanjorensis leaf extract, respectively. Groups V and VI received 400 mg/kg of T. occidentalis and J. tanjorensis leaf extracts, respectively. Group VII received extract composite (1:1). Standard techniques were used to evaluate the major anaemia indices. Findings regarding the relative anti-anaemia effectiveness of J. tanjorensis and T. occidentalis leaf extracts revealed that the extracts did not prevent the treated animals' body weight from increasing. Additionally, 200 mg/kg of the composite extract was found to significantly (p< 0.05) raise blood parameters above those reported for their respective components. PCV value recorded with 400 mg/kg bw of TOLE was considerably (p < 0.05) greater than that reported for JTLE. In conclusion, T. occidentalis had a better anti-anaemia potential.