Diagnostic laparotomy and splenectomy were performed in 30 consecutive untreated patients with Hodgkin's disease. The preoperative assessment of splenic involvement was incorrect in 33%. There were no false-negative lymphangiograms; however, 6 of 13 positive studies could not be confirmed at surgery. Involvement of abdominal nodes outside the periaortic chain was found in 5 patients. The potential therapeutic benefit of routine laparotomy and splenectomy for staging is discussed.
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Zarembok et al. (1972) studied this question.
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