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• Nine family members with hereditary retinal neovascularization showed wide variability in the extent of the clinical disorder and a slow progression of the disease process. Clinical and angiographic evaluation of these patients at various stages of their disease, and analysis of their histories points to a progressive peripheral retinal vascular disorder with secondary vitreous changes. The condition is characterized by retinal arteriolar ischemia, new vessel formation at the retinal periphery, and hemorrhage with retinal detachment.
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Gitter et al. (1978) studied this question.
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