Key result
Distal renal artery denervation using multielectrode catheters resulted in a stable decrease in blood pressure and was safe in a patient with bilateral renal artery stenosis.
Why the study?
Renovascular hypertension is severe and challenging to manage, with recent studies lacking a clear answer on whether conservative or surgical treatment is most appropriate.
Does distal renal artery denervation reduce blood pressure in a patient with bilateral renal artery stenosis and resistant hypertension?
Case Report (n=1)
Does distal renal artery denervation reduce blood pressure in a patient with bilateral renal artery stenosis and resistant hypertension?
Distal renal artery denervation may be a safe and effective alternative treatment for resistant renovascular hypertension in patients with bilateral renal artery stenosis and impaired renal function.
May support distal denervation in bilateral renal stenosis; hypothesis-generating and requires prospective trials before adoption.
Introduction. Renovascular hypertension is one of the most severe types of hypertension in terms of the choice of treatment strategy. Recent studies have not provided a clear answer to the question of which treatment approach (conservative or surgical) is most appropriate for these patients. Brief description. The presented case describes a female patient with a longterm uncontrolled hypertension, whose examination revealed bilateral renal artery stenosis. Considering the debatable clinical effectiveness of revascularization of renal artery stenosis, the patient underwent distal renal artery denervation using multielectrode catheters. A decrease in blood pressure was shown. Follow-up of the patient demonstrated stable antihypertensive effect of the procedure, as well as its safety in case of impaired renal function. Discussion. This clinical demonstrates the third way in the treatment of patients with renal arteries stenosis and resistant hypertension — renal sympathetic denervation. This method requires a separate controlled study with individuals with renal dysfunction, including renovascular origin.
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Orekhov et al. (2024) conducted a case report in Renovascular hypertension with bilateral renal artery stenosis (n=1). Distal renal artery denervation using multielectrode catheters was evaluated on Blood pressure reduction and safety. Distal renal artery denervation using multielectrode catheters resulted in a stable decrease in blood pressure and was safe in a patient with bilateral renal artery stenosis.
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