Key result
An indirect ELISA applied to individual milk demonstrated 95.0% sensitivity and 97.7% specificity for detecting BVDV antibodies compared with the virus neutralization test on serum.
Why the study?
Does an indirect ELISA on milk accurately detect BVDV antibodies and predict within-herd prevalence compared to serum virus neutralization?
Population
Bulk and individual milk samples from 117 herds located in Brittany, including 1113 matched milk/serum…
Comparison
Indirect enzyme-linked immunosorbent assay… vs Virus neutralization test on serum
Design
Cross-sectional
Authors
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Supports milk ELISA as convenient alternative for individual BVDV serology; leaves open herd-prevalence validation.
Observational (n=1,113)
Yes
Does an indirect ELISA on milk accurately detect BVDV antibodies and predict within-herd prevalence compared to serum virus neutralization?
An indirect ELISA on bulk milk is a highly sensitive and specific tool to identify herds with a low prevalence of BVDV antibody-positive cows.
Beaudeau et al. (2001) conducted an observational in Bovine viral diarrhoea virus (BVDV) (n=1,113). Indirect enzyme-linked immunosorbent assay (ELISA) on milk vs. Virus neutralization test on serum was evaluated on Sensitivity and specificity for detection of BVDV antibodies. An indirect ELISA applied to individual milk demonstrated 95.0% sensitivity and 97.7% specificity for detecting BVDV antibodies compared with the virus neutralization test on serum.
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