Key result
Shorter leg length was associated with a greater increase in systolic blood pressure with age, with a 2.1 mm Hg higher increase over 10 years for participants with 10 cm shorter legs (P<=0.001).
Why the study?
Does short stature influence the change in blood pressure as it increases with age in adults?
Cohort (n=3,035)
Does short stature influence the change in blood pressure as it increases with age in adults?
Mean Difference: -0.021 (95% CI -0.029–-0.013)
p-value: p=<=0.001
Shorter height and leg length are associated with a steeper increase in systolic blood pressure and pulse pressure during middle age, suggesting increased susceptibility to arterial aging.
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Shorter leg length may mark higher arterial aging susceptibility; hypothesis-generating and requires prospective confirmation before clinical use.
Langenberg et al. (2005) reported a cohort. Short height and leg length vs. Taller height and longer leg length was evaluated on Change in systolic blood pressure (MD -0.021 mm Hg/year per cm increase in leg length, 95% CI -0.029 to -0.013, p=<=0.001). Shorter leg length was associated with a greater increase in systolic blood pressure with age, with a 2.1 mm Hg higher increase over 10 years for participants with 10 cm shorter legs (P<=0.001).
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