Ion‐Spray Mass Spectrometry of Lipopeptide Vaccines

Its speed and accuracy and the extremely simple sample preparation required recommends ion‐spray mass spectrometry as a technique for studying highly lipophilic and amphiphilic molecules of high molecular mass and, in particular, for biomolecules (which have not previously been able to be characterized by mass spectrometry). Routine analyses detect molecular masses up to 6000 u with an accuracy of ± 1 u.