Key result
Intermittent epidural morphine showed no significant difference in postoperative pain scores compared to patient-controlled analgesia in children after orthopaedic surgery.
Why the study?
Does intermittent epidural morphine improve postoperative pain relief compared to patient-controlled analgesia with morphine in children after orthopaedic surgery?
RCT (n=40)
randomly assigned
Does intermittent epidural morphine improve postoperative pain relief compared to patient-controlled analgesia with morphine in children after orthopaedic surgery?
Epidural morphine and patient-controlled analgesia provide similar quality of pain relief in children after orthopaedic surgery, though they differ in medication requirements and side effect incidence.
Answers are grounded in this paper and cite their sources.
No advantage of intermittent epidural morphine over PCA; confirms comparable analgesia with differing side-effect and dosing profiles in children.
We compared epidural and patient-controlled analgesia using morphine for pain relief during the first 30 h after orthopaedic surgery to examine whether intermittent epidural morphine (EM) offered a clinical advantage over patient-controlled analgesia in children. Forty patients were assigned randomly to receive either EM or morphine by the patient-controlled analgesia technique. In the special care unit, trained observers evaluated the patient's level of postoperative pain with a standardized objective pain scale. The differences in pain scores among the groups were compared. The two groups were not significantly different in age, weight, duration of operation, or anesthesia. There was no significant difference in quality of pain relief except for the amount of medicine required to control postoperative pain and the incidence of side effects between the two groups.
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Goodarzi et al. (1993) conducted an RCT in Postoperative pain after orthopaedic surgery (n=40). Intermittent epidural morphine vs. Patient-controlled analgesia with morphine was evaluated on Postoperative pain scores. Intermittent epidural morphine showed no significant difference in postoperative pain scores compared to patient-controlled analgesia in children after orthopaedic surgery.
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