Key result
In patients undergoing emergency colorectal cancer surgery, 1-month postoperative mortality was significantly associated with higher tumor grade (p = 0.02) and advanced TNM staging (p = 0.026).
Observational (n=67)
Yes
In patients undergoing emergency colorectal cancer surgery, postoperative mortality is high and significantly associated with advanced tumor grade and TNM staging.
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May inform preoperative risk stratification in emergency colorectal cancer surgery; hypothesis-generating for targeted interventions.
INTRODUCTION: The aim of the present study was to establish, having adjusted for case mix, the size of the differences in postoperative mortality and 5-year survival between patients presenting as an emergency with evidence of obstruction and perforation and the association of clinicopathological factors with mortality (bivariate analyses). MATERIAL AND METHODS: The study included 67 patients who presented with colorectal cancer (CRC) between 2009 and 2013 in Iran. The mean age of the patients was 59.7 years. Of the 67 patients, 37 (55.22%) were male and 30 (44.77%) were female. Certain parameters that correlated with CRC and surgical treatment were investigated. CONCLUSIONS: Compared with patients who undergo elective surgery for colon cancer, those who present as an emergency with evidence of obstruction or perforation have higher postoperative mortality rates and poorer cancer-specific survival. Also, colorectal cancer patients with emergency surgery showed aggressive histopathology and an advanced stage.
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Talebreza et al. (2016) conducted an observational in Colorectal cancer presenting as an emergency (n=67). Advanced tumor grade and TNM staging vs. Lower tumor grade and TNM staging was evaluated on Postoperative mortality at 1 month (p=0.02). In patients undergoing emergency colorectal cancer surgery, 1-month postoperative mortality was significantly associated with higher tumor grade (p = 0.02) and advanced TNM staging (p = 0.026).
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