Key result
Emergency surgery for complicated colorectal cancer carries ~27% postoperative mortality, highest in older females with perforated tumors.
Why the study?
Demographic, clinical, and histopathological variables affecting mortality in emergency surgery for complicated colorectal cancer were not well characterized.
What demographic, clinical, and histopathological variables affect mortality in patients undergoing emergency surgery for complicated colorectal cancer?
Observational (n=33)
No
What demographic, clinical, and histopathological variables affect mortality in patients undergoing emergency surgery for complicated colorectal cancer?
In patients undergoing emergency surgery for complicated colorectal cancer, high mortality is associated with female sex, age over 60, left-sided tumors, synchronous tumors, and perforation, suggesting unnecessary major resections should be avoided.
May inform risk stratification for emergency colorectal cancer surgery; hypothesis-generating and should not yet change practice.
AIM: To evaluate retrospectively demographic, clinical and histopathological variables effective on mortality in patients who had undergone emergency surgery due to complicated colorectal cancer. METHODS: A total of 39 patients underwent urgent surgical interventions due to complicated colorectal cancer at the Department of General Surgery, Dursun Odabaş Medical Center, between January 2010 and January 2015. Thirty three of these were included in the study. Six patients were excluded because complete medical records had been missing. Medical records of the 33 cases were retrospectively reviewed. RESULTS: There were 14 (42.5%) male and 19 (57.5%) female patients. Mean age was 60 years (range: 32- 83 years); 14 (42.5%) patients were less than 60 years old , while 19 (57.5%) were 60 years old or older. Operations were performed due to perforation (39.3%) and obstruction (60.6%) in 13 and 20 patients, respectively. Tumor localization was in the right and transverse colon in nine (21.2%) and in the left colon in 24 cases (72.7%). Eleven (33.3%) patients underwent resection and anastomosis, 13 (39.3%) resection and ostomy, and nine (27.2%) patients underwent ostomy alone without any resection. Postoperative mortality occurred in nine cases (27.2%). CONCLUSIONS: High mortality should be expected in females older than 60 years with a left sided colon tumor or with another synchronous tumor and in perforated tumors. Unnecessary major resections should be avoided and primary pathology should be in the focus of treatment in order to decrease the mortality and morbidity rates.
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Kızıltan et al. (2015) conducted an observational in Complicated colorectal cancer (n=33). Emergency surgery was evaluated on Postoperative mortality. In patients undergoing emergency surgery for complicated colorectal cancer, postoperative mortality was 27.2%, with higher mortality expected in females over 60 with left-sided or perforated tumors.
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