Key result
Emergency colorectal cancer surgery in elderly patients is linked to a ~66% postoperative complication rate.
Why the study?
Complicated colorectal cancer often requires emergency treatment in elderly patients, but their clinical profile and factors associated with worse short-term prognosis required evaluation.
What are the outcomes and prognostic factors in elderly patients undergoing emergency surgery for complicated colorectal cancer?
Cohort (n=67)
No
What are the outcomes and prognostic factors in elderly patients undergoing emergency surgery for complicated colorectal cancer?
Elderly patients undergoing emergency surgery for complicated colorectal cancer face high morbidity (65.7%) and 30-day mortality (10.4%), with advanced age being a significant risk factor.
Answers are grounded in this paper and cite their sources.
Advanced age signals elevated short-term morbidity and mortality after emergency CRC surgery; leaves open need for prospective risk-stratification studies before guiding practice.
OBJECTIVE: Colorectal cancer is one of the most frequent types of malignant neoplasms. Age is a risk factor for this disease, with 75% of cases diagnosed in patients older than 65 years. Complications such as obstruction, hemorrhage, and perforation are present in more than one-third of cases and require emergency treatment. We aim to analyze the profile of elderly patients undergoing surgery for complicated colorectal cancer, and to evaluate factors related to worse short-term prognosis. METHODS: A retrospective analysis of patients who underwent emergency surgical treatment for complicated colorectal cancer was performed. Demographics, clinical, radiological and histological data were collected. RESULTS: Sixty-seven patients were analyzed. The median age was 72 years, and almost half (46%) of the patients were female. Obstruction was the most prevalent complication at initial presentation (72%). The most common sites of neoplasia were the left and sigmoid colon in 22 patients (32.8%), and the right colon in 17 patients (25.4%). Resection was performed in 88% of cases, followed by primary anastomosis in almost half. The most frequent clinical stages were II (48%) and III (22%). Forty-three patients (65.7%) had some form of postoperative complication. Clavien-Dindo grades 1, 2, and 4, were the most frequent. Complete oncologic resection was observed in 80% of the cases. The thirty-day mortality rate was 10.4%. Advanced age was associated with worse morbidity and mortality. CONCLUSION: Elderly patients with complicated colorectal cancer undergoing emergency surgery have high morbidity and mortality rates. Advanced age is significantly associated with worse outcomes.
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Menegozzo et al. (2019) conducted a cohort in Complicated colorectal cancer (n=67). Emergency surgery was evaluated on Postoperative complications (morbidity). Elderly patients undergoing emergency surgery for complicated colorectal cancer experienced a high postoperative complication rate of 65.7% and a 30-day mortality rate of 10.4%, with advanced age significantly associated with worse outcomes.
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