Diarrhea Associated with Clostridium Perfringens Type A Enterotoxin in Neonatal Pigs

2,7,12 but has not been reported in the United States. In this report, we describe the clinical, microbiological, and histological features of an epizootic of neonatal pig diarrhea associated with the overgrowth of spore-bearing C. perfringens type A in the small intestine. A 120-sow, continuously farrowing swine unit from southcentral Minnesota experienced an epizootic of diarrhea in l3-day-old pigs. Clinical illness, which usually began shortly after birth, was characterized by high morbidity (nearly 100%) and negligible mortality (< 1%). Scouring pigs remained vigorous, continued to nurse, and recovered spontaneously in approximately 4 days. Diarrhea was clinically nonresponsive to treatment with gentamicin or trimethoprim-sulfadimeth