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• Evaluated associations between adverse childhood experiences (ACEs) and prenatal hypothalamic-pituitary-adrenal (HPA) axis • Maternal ACEs were associated with increased cortisol at 30 min post waking and a flattened diurnal slope • Maternal ACEs were associated with a progressive steepening of the daytime cortisol slope with advancing gestation • The findings have implications for the intergenerational transmission of maternal ACEs
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Thomas et al. (2018) studied this question.
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