Key result
Among 64 patients with myocardial infarction and left main disease, only 5% had isolated left main disease, while 95% had concurrent 1-, 2-, or 3-vessel disease.
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Left main coronary artery disease rarely occurs in isolation, suggesting that its familial aggregation reflects the heritability of severe, multi-vessel coronary artery disease rather than a location-specific phenomenon.
Patel et al. (2008) conducted a letter in Left main coronary artery disease and myocardial infarction (n=64). Left main coronary artery disease was evaluated on Presence of concurrent 1-vessel, 2-vessel, or 3-vessel disease. Among 64 patients with myocardial infarction and left main disease, only 5% had isolated left main disease, while 95% had concurrent 1-, 2-, or 3-vessel disease.