Left Atrial Strain Prediction of New-Onset Atrial Fibrillation in Apical Hypertrophic Cardiomyopathy with Cardiac MRI

Q: What is the clinical evidence from this study?

Study design: Observational. Population: Apical hypertrophic cardiomyopathy (AHCM). Intervention: Cardiac MRI-derived left atrial strain (LAS). Primary outcome: New-onset atrial fibrillation (AF).

Q: What does this research mean for the field?

Cardiac MRI-derived left atrial strain is independently associated with new-onset atrial fibrillation in patients with apical hypertrophic cardiomyopathy. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

Yipei Song; Mengyao Hu; Tian Zheng; Xiwen Wang; Qimin Fang; Ziyan Feng; Lianggeng Gong

doi:10.1148/ryct.250266

August 1, 2026Radiology Cardiothoracic Imaging

Left Atrial Strain Prediction of New-Onset Atrial Fibrillation in Apical Hypertrophic Cardiomyopathy with Cardiac MRI

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Key result

Cardiac MRI left atrial strain evaluated for predicting new-onset AF in apical HCM.

Why the study?

Does cardiac MRI-derived left atrial strain predict new-onset atrial fibrillation in patients with apical hypertrophic cardiomyopathy?

Key Points

To evaluate the predictive value of cardiac MRI-derived left atrial strain for new-onset atrial fibrillation in patients with apical hypertrophic cardiomyopathy.
Retrospective review of patients with apical hypertrophic cardiomyopathy and no history of atrial fibrillation who underwent 3.0-T cardiac MRI between May 2016 and December 2023.
Assessed left atrial strain metrics—reservoir strain, conduit strain, and booster pump strain—alongside minimum left atrial volume index.
Assessed cardiac MRI-derived left atrial strain parameters as potential noninvasive imaging markers for predicting new-onset atrial fibrillation.

Study Design

Type

Observational

Structured PICO

Does cardiac MRI-derived left atrial strain predict new-onset atrial fibrillation in patients with apical hypertrophic cardiomyopathy?

P

Population

Patients with apical hypertrophic cardiomyopathy and no prior history of atrial fibrillation who underwent 3.0-T cardiac MRI.

E

Exposure

Cardiac MRI-derived left atrial strain (LAS) parameters (reservoir strain, conduit strain, booster pump strain) and minimum left atrial volume index (LAVI)

O

Outcome

New-onset atrial fibrillation (AF)hard clinical

Cardiac MRI-derived left atrial strain is being evaluated for its predictive value for new-onset atrial fibrillation in patients with apical hypertrophic cardiomyopathy.

Implication

May support AF risk stratification in apical HCM; leaves open prospective validation before clinical use.

Abstract

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Discussion

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Cite This Study

Song et al. (2026) conducted an observational in Apical hypertrophic cardiomyopathy (AHCM). Cardiac MRI-derived left atrial strain (LAS) was evaluated on New-onset atrial fibrillation (AF). The study evaluated cardiac MRI-derived left atrial strain for predicting new-onset atrial fibrillation in apical hypertrophic cardiomyopathy, but results were not provided in the truncated abstract.

synapsesocial.com/papers/6a9affdcc50b4e45c77c4f7e https://doi.org/10.1148/ryct.250266

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Left Atrial Strain Prediction of New-Onset Atrial Fibrillation in Apical Hypertrophic Cardiomyopathy with Cardiac MRI

Key Points

Study Design

Structured PICO

Implication

Abstract

Discussion

Cite This Study

Left Atrial Strain Prediction of New-Onset Atrial Fibrillation in Apical Hypertrophic Cardiomyopathy with Cardiac MRI

Key Points

Study Design

Structured PICO

Implication

Abstract

Discussion

Cite This Study

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