May 17, 2005Catheterization and Cardiovascular Interventions
Underexpansion of sirolimus‐eluting stents: Incidence and relationship to delivery pressure
Why the study?
Does increasing balloon delivery pressure improve the expansion of sirolimus-eluting stents in patients with native coronary artery narrowing?
Population
51 patients (53 lesions) with native coronary artery narrowing
Design
Cohort
Authors
Discussion
Loading...
Member takes
Implication
Higher balloon pressure was associated with improved sirolimus-eluting stent expansion; leaves open whether this improves clinical outcomes.
Structured PICO
Does increasing balloon delivery pressure improve the expansion of sirolimus-eluting stents in patients with native coronary artery narrowing?
P
Population
51 patients (53 lesions) with native coronary artery narrowing
I
Intervention
Balloon-expandable sirolimus-eluting stents serially expanded with gradual balloon inflations (14 atm, 20 atm, and optional postdilatation with 0.5 mm larger balloon)
O
Outcome
Stent expansion (minimal stent cross-sectional area [CSA]/reference lumen CSA) and adequate expansion by MUSIC criteria assessed by intravascular ultrasound (IVUS)surrogate
Sirolimus-eluting stent underexpansion is common at conventional pressures, and increasing balloon delivery pressure to 20 atm significantly improves stent expansion.
Cite This Study
Cheneau et al. (2005) studied this question.