Proliferation of Fibroblast-like Cells on Failing Intraocular Lenses

SUMMARY The process of reactivation and multifocal proliferation of fibroblast-like cells near giant cells on the surface of a well-developed cellular membrane covering a Choyce anterior chamber lens implant is described histologically in an eye that had a good surgical result at first and later developed bullous keratopathy, corneal ulceration, and final rupture three years following surgery. This is compared with another eye with a late stage of scarformation surrounding a Choyce implant two and a half years after implantation with severe complications. Details of lens implant cytology are demonstrated and discussed.