Easily prepared allyl phenyl sulfones, capable of introduction of the alkene by electrophilic alpha-substitution, are superior to allyl acetates as substrates for Pd-catalyzed Zn-ene cyclizations, providing C5 or C(4)N rings with cis-1,2-vinyl and -CH(2)Zn substituents. Several examples, with different methods of substrate preparation, are presented. [reaction: see text]
No takes yet. Share an insight, caveat, or question.
Deng et al. (2005) studied this question.
Synapse has enriched 5 related papers. Consider them for comparative context: