The observation has been confirmed that yellow mice on continued inbreeding no longer become obese if maintained under the usual laboratory conditions. 2. Feeding a diet of the “synthetic” type made it possible to induce obesity in the yellow mice but not in their non—yellow litter—mates. 3. The obese yellow mice were observed to have fatty livers. Two of these animals were found to have liver tumors.
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Fenton et al. (1951) studied this question.