Key result
Surgical resection of a cervical polypoid tumor in an 8-year-old girl revealed an alveolar soft part sarcoma with characteristic histological, ultrastructural, and immunohistochemical features.
Case Report (n=1)
This report describes the rare presentation and immunohistochemical profile of an alveolar soft part sarcoma in the uterine cervix of a pediatric patient.
Raises awareness for alveolar soft part sarcoma in pediatric cervical masses; extends the documented spectrum of this rare tumor.
A rare case of an alveolar soft part sarcoma of the uterine cervix in an 8 year old girl is presented. The patient was admitted because of genital bleeding lasting for 7 months. A polypoid tumor, 2 x 1.5 cm in diameter, was found in her external uterine os and was surgically resected. Microscopically, the tumor consisted of a uniform sheet of tumor cells in the cytoplasm which contained granules and which were stained with periodic acid-Schiff, both before and after the diastase digestion. Alveolar arrangement of the tumor cells was manifested with reticulin silver impregnation. Dense, membrane bound granules were evident at an ultrastructural level in the cytoplasm of the tumor cells. An immunohistochemical examination demonstrated a positive reaction for anti-desmin, anti-myoglobin, anti-HHF35 and anti-neuron specific enolase in the cytoplasm.
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Morimitsu et al. (1993) conducted a case report in Alveolar soft part sarcoma of the uterine cervix (n=1). Surgical resection was evaluated on Histological, ultrastructural, and immunohistochemical characteristics. Surgical resection of a cervical polypoid tumor in an 8-year-old girl revealed an alveolar soft part sarcoma with characteristic histological, ultrastructural, and immunohistochemical features.