Key result
Previous multiple percutaneous coronary interventions were associated with significantly lower mean volumetric blood flow rate in coronary bypass grafts (29.5 vs 48.2 ml/min, p=0.0001).
Why the study?
Coronary bypass graft function depends on the state of target coronary arteries, but the impact of multiple previous percutaneous coronary interventions on graft function assessed by ultrasonic flowmetry was unclear.
Does a history of multiple percutaneous coronary interventions reduce the functional status of coronary bypass grafts measured by ultrasonic flowmetry in patients undergoing surgical myocardial revascularization?
Population
47 patients undergoing coronary artery bypass surgery
Comparison
Multiple previous PCI vs no previous PCI
Design
Retrospective study
Authors
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Multiple prior PCIs were associated with lower graft flow; leaves open whether this reflects direct effects or confounding in observational data.
Cohort (n=47)
Does a history of multiple percutaneous coronary interventions reduce the functional status of coronary bypass grafts measured by ultrasonic flowmetry in patients undergoing surgical myocardial revascularization?
Absolute Event Rate: 29.5% vs 48.2%
p-value: p=0.0001
A history of multiple percutaneous coronary interventions is associated with reduced functional status of coronary bypass grafts during subsequent surgical revascularization.
Затолокин et al. (2023) conducted a cohort in Coronary heart disease (n=47). History of multiple percutaneous coronary interventions (PCI) vs. No previous PCI was evaluated on Mean volumetric blood flow rate (ml/min) (p=0.0001). Previous multiple percutaneous coronary interventions were associated with significantly lower mean volumetric blood flow rate in coronary bypass grafts (29.5 vs 48.2 ml/min, p=0.0001).
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