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December 22, 2016New Journal of Chemistry

Mixed-ligand copper( ii ) Schiff base complexes: the vital role of co-ligands in DNA/protein interactions and cytotoxicity

Sellamuthu Kathiresan Subramanian Mugesh Maruthamuthu Murugan

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Abstract

Four new mixed-ligand copper( ii ) complexes display an antibacterial mechanism of cell death via cell-wall rupture and cytotoxicity via apoptotic cell death.

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Kathiresan et al. (2016) studied this question.

synapsesocial.com/papers/6a9b2b1dc83a62ea3c69fe0a https://doi.org/10.1039/c6nj03501a

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Mixed-Ligand Copper(II) Maltolate Complexes: Synthesis, Characterization, DNA Binding and Cleavage, and CytotoxicityOriginal Research · 2009 · 172 citations
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3Ternary Copper Complexes for Photocleavage of DNA by Red Light: Direct Evidence for Sulfur-to-Copper Charge Transfer and d−d Band InvolvementOriginal Research · 2003 · 275 citations
4Photocontrol of Spatial Orientation and DNA Cleavage Activity of Copper(II)-Bound Dipeptides Linked by an Azobenzene DerivativeOriginal Research · 2008 · 43 citations
5Synthesis, X-ray crystal structures, magnetism, and DNA cleavage properties of copper(ii) complexes with 1,4-tpbd ligandOriginal Research · 2009 · 43 citations

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