Key result
The feasibility of mitral valve repair in active infective endocarditis was not associated with operative timing, remaining at 55% to 59% across urgent, acute, and subacute phases, although urgent surgery within 48 hours was associated with higher rates of major complications (86%).
Why the study?
The study evaluated the association between operative timing and the feasibility of mitral valve repair in active infective endocarditis.
Does operative timing affect the feasibility of mitral valve repair and operative outcomes in patients with active infective endocarditis?
Cohort (n=49)
No
Does operative timing affect the feasibility of mitral valve repair and operative outcomes in patients with active infective endocarditis?
Absolute Event Rate: 57% vs 59%
p-value: p=0.927
In active infective endocarditis, the feasibility of mitral valve repair depends on the extent of valve destruction rather than operative timing, though urgent surgery within 48 hours carries significantly higher mortality and morbidity.
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Ultra-early surgery in active IE was associated with higher mortality despite similar repair rates; leaves open optimal timing for prospective trials.
Omoto et al. (2022) conducted a cohort in Active infective endocarditis (n=49). Operative timing (within 48 hours) vs. Operative timing (3-14 days or ≥15 days) was evaluated on Frequency of mitral valve repair (p=0.927). The feasibility of mitral valve repair in active infective endocarditis was not associated with operative timing, remaining at 55% to 59% across urgent, acute, and subacute phases, although urgent surgery within 48 hours was associated with higher rates of major complications (86%).
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