Carcinoma of the lung is the leading cause of death from cancer in Western countries. Surgery is the treatment most likely to result in the cure of early non–small-cell lung carcinoma, which includes squamous-cell carcinoma, adenocarcinoma, and large-cell carcinoma. In contrast, at presentation small-cell lung cancer (oat-cell carcinoma) has almost always spread, and patients with this form of lung cancer are not candidates for resection. Since tumor involvement of mediastinal lymph nodes limits the chance of a surgical cure of non–small-cell lung cancer, accurate staging of disease in the mediastinum is essential. For patients with disease classified as stage I . . .
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Berlangieri et al. (2000) studied this question.
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