Key result
Critical illness-related corticosteroid insufficiency is a complex condition that can significantly worsen hemodynamics and survival in patients after cardiac surgery and cardiologic emergencies.
Why the study?
The specific issues of CIRCI in patients after cardiac surgery and cardiology emergencies remain largely under-recognized.
CIRCI should be considered in cardiac surgery and intensive cardiology patients presenting with refractory shock and severe hypoglycemia, as it may significantly impact survival.
CIRCI may underlie refractory shock with hypoglycemia in cardiac emergencies; hypothesis-generating from case reports, prospective studies needed before practice implications.
Critical illness - related corticosteroid insufficiency (CIRCI) is associated with elevated level of circulating biomarkers of inflammation, pro - coagulant effects, deterioration of systemic inflammatory response syndrome (SIRS) and, consequently, prolonged in - hospital stay and increased mortality of intensive care patients. Incidence of CIRCI widely varies depending on specific patient's population and applied diagnostic thresholds being as high as 30% among postoperative patients on inotropes. CIRCI is a complex clinical and pathophysiological condition with substantial influence on immediate survival and prognosis. Clinical impact of CIRCI as well as pathogenetically based therapy arouse keen interest of intensive care specialists and clinical pathologists. The specific issues of CIRCI in patients after cardiac surgery and cardiology emergencies remain largely under - recognized, so further scrutinization is needed.
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Комлев et al. (2019) conducted a review in Critical illness-related corticosteroid insufficiency (CIRCI). Critical illness-related corticosteroid insufficiency was evaluated. Critical illness-related corticosteroid insufficiency is a complex condition that can significantly worsen hemodynamics and survival in patients after cardiac surgery and cardiologic emergencies.
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