What is the clinical evidence from this study?

Study design: Cohort. Population: stable heart failure (n=112). Intervention: Increase in QRS duration over time vs. < 5% change in QRS duration. Primary outcome: mortality (p=0.001).

July 1, 2002HeartOpen Access

Arrhythmogenic giant submitral left ventricular diverticulum

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Key result

An increase in QRS duration over time predicted mortality in elderly patients with stable heart failure (P=0.001), with a >20% increase associated with the worst prognosis.

Authors

TYTetsuya YoshidaShiga University of Medical Science SNShinichi NiwanoElectrophysiology TIThoru IzumiKitasato University

Discussion

Member takes

Implication

May inform risk stratification in elderly stable HF; hypothesis-generating and requires prospective validation.

Study Design

Type

Cohort (n=112)

PICO

Population

112 elderly patients with stable heart failure followed for a mean of 27 months after two ECG measurements taken at least 12 months apart.

Exposure / Comparator

Increase in QRS duration over time vs < 5% change in QRS duration

Primary Outcome

mortality, p=0.001

Main Result

p-value: p=0.001

Cite This Study

Yoshida et al. (2002) conducted a cohort in stable heart failure (n=112). Increase in QRS duration over time vs. < 5% change in QRS duration was evaluated on mortality (p=0.001). An increase in QRS duration over time predicted mortality in elderly patients with stable heart failure (P=0.001), with a >20% increase associated with the worst prognosis.

synapsesocial.com/papers/6a9b50c36fe41f06233afbf7 https://doi.org/10.1136/heart.88.1.52

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July 1, 2002HeartOpen Access

Arrhythmogenic giant submitral left ventricular diverticulum

View Full Paper

Ask AI

Bookmark

Key result

An increase in QRS duration over time predicted mortality in elderly patients with stable heart failure (P=0.001), with a >20% increase associated with the worst prognosis.

Authors

TYTetsuya YoshidaShiga University of Medical Science SNShinichi NiwanoElectrophysiology TIThoru IzumiKitasato University

Discussion

Member takes

Implication

May inform risk stratification in elderly stable HF; hypothesis-generating and requires prospective validation.

Study Design

Type

Cohort (n=112)

PICO

Population

112 elderly patients with stable heart failure followed for a mean of 27 months after two ECG measurements taken at least 12 months apart.

Exposure / Comparator

Increase in QRS duration over time vs < 5% change in QRS duration

Primary Outcome

mortality, p=0.001

Main Result

p-value: p=0.001

Cite This Study

synapsesocial.com/papers/6a9b50c36fe41f06233afbf7 https://doi.org/10.1136/heart.88.1.52

Also Consider

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