Key result
Intradialytic hypertension occurred in 48.36% of hemodialysis sessions and was significantly associated with factors including hypertension, blood transfusion, and use of multiple antihypertensive drugs.
Cohort (n=176)
No
Intradialytic hypertension is highly prevalent among hemodialysis patients in Cameroon, highlighting the need for targeted management strategies such as dry weight reduction and optimized antihypertensive therapy.
Intradialytic hypertension links to several factors in hemodialysis; hypothesis-generating and requires prospective validation before guiding management.
Background: Hemodialysis (HD) is a therapy during which complications such as intradialytic hypertension (IDH) are frequent. We aimed to determine the incidence of IDH and associated factors amongst patients on maintenance hemodialysis in Cameroon. Method: It was a prospective cohort study including end stage kidney disease patients on HD. Data collected were: socio-demographic, comorbidities, current medication, weight, heart rate ultrafiltration rate (UF), albuminemia and electrocardiogram. The first blood pressure (BP) measurement was obtained at the beginning of the session and the last at the end. IDH was defined as an increase in systolic BP ≥ 10 mmHg between the first and the last measurement. Logistic regression was used to look for associated factors, p-value Results: Mean age was 49.06 ± 13.97 years with 64.2% males. Mean number of dialysis session was 11.26 ± 2.49. Incidence of IDH was 48.36%. The median number of IDH episodes was 5 (Range 0 - 12). Factors increasing the risk were hypertension (p = 0.003), number of antihypertensive drugs ≥ 2 (p Conclusion: IDH is frequent amongst patients on maintenance hemodialysis in our setting, with various patients related factors associated.
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Patrice et al. (2018) conducted a cohort in End stage kidney disease on hemodialysis (n=176). Risk factors for intradialytic hypertension was evaluated on Incidence of intradialytic hypertension (increase in systolic BP ≥ 10 mmHg). Intradialytic hypertension occurred in 48.36% of hemodialysis sessions and was significantly associated with factors including hypertension, blood transfusion, and use of multiple antihypertensive drugs.
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