Key result
Acute Epstein-Barr virus infection can cause localized brain-stem encephalitis, which in this case resolved rapidly without treatment but left mild neurologic sequelae at 6 months.
Case Report (n=1)
This case report describes localized brain-stem involvement as an unusual complication of Epstein-Barr virus infection.
EBV brainstem encephalitis may resolve spontaneously with mild sequelae; leaves open incidence, risk factors, and management in children.
A case of brain-stem encephalitis with strong serologic evidence of acute Epstein-Barr virus infection is described. Recovery was rapid without treatment, but mild neurologic sequelae were seen at 6-month follow-up. Epstein-Barr virus infection in childhood may be asymptomatic and heterophil antibody negative. Encephalitis is an unusual but well-recognized complication of Epstein-Barr virus infection, but localized brain-stem involvement, to our knowledge, has not been previously described.
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North et al. (1993) conducted a case report in Brain-stem encephalitis caused by Epstein-Barr virus (n=1). Epstein-Barr virus infection was evaluated on Recovery and neurologic sequelae. Acute Epstein-Barr virus infection can cause localized brain-stem encephalitis, which in this case resolved rapidly without treatment but left mild neurologic sequelae at 6 months.
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