Key result
The Norwood procedure was associated with equivalent global RV pump function compared to the hybrid approach (59% vs 59%, p=0.91), but superior pulmonary artery development and fewer reinterventions.
Why the study?
Does the Norwood procedure improve right ventricular function and pulmonary artery dimensions compared to the hybrid procedure in survivors with hypoplastic left heart syndrome?
Population
86 survivors with hypoplastic left heart syndrome evaluated by cardiac magnetic resonance after stage II…
Comparison
Norwood procedure vs Hybrid procedure
Design
Cohort
Follow-up
Evaluated after stage II palliation prior to planned…
Authors
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Norwood associated with better RV strain and larger pulmonary arteries than hybrid in HLHS survivors; hypothesis-generating and should not yet change practice.
Cohort (n=86)
Does the Norwood procedure improve right ventricular function and pulmonary artery dimensions compared to the hybrid procedure in survivors with hypoplastic left heart syndrome?
Absolute Event Rate: 59% vs 59%
p-value: p=0.91
While both Norwood and hybrid palliations for HLHS result in preserved global RV pump function, the Norwood approach is associated with better RV myocardial deformation, larger pulmonary arteries, and fewer reinterventions.
Latus et al. (2017) conducted a cohort in Hypoplastic left heart syndrome (HLHS) (n=86). Norwood procedure vs. Hybrid procedure was evaluated on Global RV pump function (p=0.91). The Norwood procedure was associated with equivalent global RV pump function compared to the hybrid approach (59% vs 59%, p=0.91), but superior pulmonary artery development and fewer reinterventions.
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