Key result
Great saphenous vein leiomyosarcoma is an extremely rare malignancy that was misdiagnosed clinically in 43% of reported cases, highlighting the need for a high index of suspicion.
Why the study?
Great saphenous vein leiomyosarcoma is an extremely rare vascular leiomyosarcoma subgroup with fewer than 50 reported cases, frequently misdiagnosed clinically due to lack of specific established radiologic findings.
Case Report (n=1)
Masses presenting along the course of vessels should be suspected for malignancy to avoid misdiagnosis and multiple surgeries.
Maintain high suspicion for great saphenous vein masses to avoid LMS misdiagnosis as aneurysm; case reports leave diagnostic criteria open.
Vascular leiomyosarcoma LMS. is an extremely rare subgroup of LMSs. Fewer than 50 cases of LMS originating from the great saphenous vein have been reported. In 43% of reported cases, LMS was misdiagnosed clinically. In our case, the patient was initially misdiagnosed as having a thrombosed aneurysm. This misdiagnosis could be due to the rarity of great saphenous vein LMS cases, for which a high index of suspicion is needed, and because no specific radiologic findings have been established for diagnosing LMSs. Masses presenting along the course of vessels should be suspected for malignancy, which can be helpful in performing definitive surgery and avoiding multiple surgeries.
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Atieh et al. (2023) conducted a case report in Great saphenous vein leiomyosarcoma (n=1). Great saphenous vein leiomyosarcoma was evaluated. Great saphenous vein leiomyosarcoma is an extremely rare malignancy that was misdiagnosed clinically in 43% of reported cases, highlighting the need for a high index of suspicion.
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