Key result
Hepatitis C virus nonstructural protein 4B is an integral membrane protein that induces the membranous web, interacts with viral RNA and proteins, and plays a key role in viral assembly.
Population
Hepatitis C virus (HCV) nonstructural protein 4B (NS4B)
Design
Review
Authors
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May guide NS4B inhibitor development; leaves open clinical translation in chronic hepatitis C.
Further understanding of HCV NS4B structure and function may reveal new opportunities for antiviral interventions against chronic hepatitis C.
Gouttenoire et al. (2010) conducted a review in Hepatitis C. Hepatitis C virus nonstructural protein 4B (NS4B) was evaluated. Hepatitis C virus nonstructural protein 4B is an integral membrane protein that induces the membranous web, interacts with viral RNA and proteins, and plays a key role in viral assembly.
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