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September 1, 2004Irish Veterinary JournalOpen Access

A survey of antibodies to pestivirus in sheep in the Republic of Ireland

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Key result

A national survey found that 5.6% of adult ewes and 46.0% of sheep flocks in the Republic of Ireland were seropositive for pestivirus antibodies.

Population

1,448 adult ewes from 91 flocks, representing all 26 counties in the Republic of Ireland

Design

Cross-sectional

Authors

RORonan O’NeillUniversity Hospital GalwayMOMichael B. O’ConnorUniversity of MinnesotaPOPatrick O’ReillyLiverpool John Moores University

Discussion

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Overview

Indicates pestivirus exposure in Irish sheep flocks; leaves open the need for species-specific surveillance and BVDV differentiation studies.

Study Design

Type

Cross-Sectional (n=1,448)

Structured PICO

P
Population
1,448 adult ewes from 91 flocks across the Republic of Ireland tested for pestivirus antibodies.
O
Outcome
Seroprevalence of pestivirus antibodies (IgG1 antibody to border disease virus)surrogate

The study demonstrates a 5.6% seroprevalence of pestivirus antibodies among sheep in the Republic of Ireland, suggesting that bovine viral diarrhoea virus (BVDV) may be the major ruminant pestivirus infecting sheep in the region.

Limitations

  • Antibodies may become undetectable over time, potentially underestimating pestivirus activity.
  • High proportion of farms with cattle (92%) prevented full evaluation of cattle-to-sheep transmission.
  • Did not distinguish flocks with higher numbers of non-indigenous breeds.
  • Inability to fully test the relationship between the concurrent presence of cattle and levels of ovine pestivirus seroconversion because cattle were present on a very high proportion (92%) of the farms tested.

Cite This Study

O’Neill et al. (2004) conducted a cross-sectional in Pestivirus infection (n=1,448). Pestivirus exposure was evaluated on Seroprevalence of pestivirus antibodies (95% CI 4.4-6.8). A national survey found that 5.6% of adult ewes and 46.0% of sheep flocks in the Republic of Ireland were seropositive for pestivirus antibodies.

synapsesocial.com/papers/6a9b7fcfcd9747862c3a0d86https://doi.org/10.1186/2046-0481-57-9-525
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Also Consider

Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Survey for antibodies to respiratory viruses in two groups of sheep in Northern Ireland1984 · 26 citations
  2. 2Border disease in sheep caused by transmission of virus from cattle persistently infected with bovine virus diarrhoea virus1991 · 117 citations