Key result
Electromechanical mapping of left ventricular function demonstrated 73% and 79% concordance with echocardiography for local shortening (AUC 0.75) and unipolar voltage (AUC 0.81).
Why the study?
Does catheter-based electromechanical mapping accurately assess regional left ventricular function compared to echocardiography in patients with normal ventricles or old infarcts?
Observational (n=10)
Does catheter-based electromechanical mapping accurately assess regional left ventricular function compared to echocardiography in patients with normal ventricles or old infarcts?
Catheter-based electromechanical mapping provides regional ventricular function assessment that correlates well with echocardiography, potentially aiding in the localization of catheter-based therapies.
Moderate concordance supports electromechanical mapping for regional LV research; hypothesis-generating and should not yet change practice.
A catheter-based method of mapping left ventricular electromechanical regional function may be used to optimize application of local myocardial therapies by demarcating zones of ischemia or infarction. We thus performed a detailed comparison between electromechanical parameters and segmental function as assessed by echocardiography in 10 patients (3 with normal ventricles and 7 with old infarcts). Using a 16-segment model, unipolar voltage and local shortening were significantly and independently related to echo score by multivariate analysis, having a concordance with echo score of 73% for shortening and 79% for voltage. Area under ROC curves, expressing the ability to differentiate normal from abnormal segments, had values of 0.75 and 0.81 for local shortening and unipolar voltage, respectively. In conclusion, automatic assessment of regional ventricular function can be achieved independently by electrical and mechanical parameters, compared with echocardiography, permitting an integrated approach to the evaluation of ventricular function and aiding localization of catheter-based therapies.
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Lessick et al. (2000) conducted an observational in Left ventricular regional function (n=10). Electromechanical mapping vs. Echocardiography was evaluated on Concordance with echo score and area under ROC curves. Electromechanical mapping of left ventricular function demonstrated 73% and 79% concordance with echocardiography for local shortening (AUC 0.75) and unipolar voltage (AUC 0.81).
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