Key result
Epidural administration of 0.125% bupivacaine with 0.0002% fentanyl provided similar analgesia to 0.25% plain bupivacaine while minimizing motor block.
Why the study?
Labour pain is severe and can negatively affect the mother, fetus, and labour outcome, prompting evaluation of different epidural analgesic regimens.
Does epidural 0.125% bupivacaine with 0.0002% fentanyl improve analgesia and reduce motor block compared to 0.25% plain bupivacaine in parturients during labor?
Does epidural 0.125% bupivacaine with 0.0002% fentanyl improve analgesia and reduce motor block compared to 0.25% plain bupivacaine in parturients during labor?
Adding fentanyl to a lower concentration of bupivacaine for epidural labor analgesia provides equivalent pain relief while preserving motor function compared to higher concentration plain bupivacaine.
May support lower-dose epidural regimens in labor; leaves open need for confirmatory RCTs before practice change.
Introduction: Labour pain is of major concern since most parturients experience signicant pain of extremely severe intensity. Labour pain can have deleterious effects on the mother, on the foetus and on the labour outcome. Epidural anaesthesia is an effective means of providing analgesia during labour. To compare the efcacy of epidural analgesia using 0.125% bupivacaine and 0.0002% Aim: fentanyl versus an epidural using 0.25% bupivacaine alone for labour analgesia. It is a prospective comparative study c Methods: onducted at a Tertiary care hospital, Fifty parturients who were admitted to the antenatal ward and who requested pain relief during labor and who fullled the inclusion criteria were selected for the study after taking written informed consent. Analgesia provided by both techniques Conclusion: was found to be similar. Women in group FB retained motor power in their legs. Motor Block was minimized in Group FB. Both the intervention group had lesser impact on the hemodynamics. Complications were minor and were easily managed.
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Kumar et al. (2023) studied Labour pain (n=50). Epidural 0.125% bupivacaine with 0.0002% fentanyl vs. Epidural 0.25% plain bupivacaine was evaluated on Analgesia efficacy. Epidural administration of 0.125% bupivacaine with 0.0002% fentanyl provided similar analgesia to 0.25% plain bupivacaine while minimizing motor block.
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