Key result
Significant histological abnormalities on endomyocardial biopsy were found in 46% of patients with pure apical hypertrophy, an incidence similar to other types of hypertrophic cardiomyopathy.
Why the study?
Does apical hypertrophic cardiomyopathy have distinct clinicopathological and endomyocardial biopsy features compared to other types of hypertrophic cardiomyopathy?
Observational (n=87)
No
Does apical hypertrophic cardiomyopathy have distinct clinicopathological and endomyocardial biopsy features compared to other types of hypertrophic cardiomyopathy?
Answers are grounded in this paper and cite their sources.
Apical hypertrophic cardiomyopathy shares histological features with other forms of HCM, supporting its classification as a subtype of HCM, and left ventricular biopsy is more sensitive than right ventricular biopsy for its diagnosis.
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Seiryo Kobayashi (1995) conducted an observational in Hypertrophic cardiomyopathy (n=87). Apical hypertrophy (APH) vs. Other types of hypertrophic cardiomyopathy was evaluated on Significant abnormality on endomyocardial biopsy (myocyte hypertrophy and disarray). Significant histological abnormalities on endomyocardial biopsy were found in 46% of patients with pure apical hypertrophy, an incidence similar to other types of hypertrophic cardiomyopathy.
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