IN ONE OF OUR PATIENTS portal vein throm-bosis complicating malignant hepatoma was diagnosed by splenoportography and confirmed by postmortem examination. This prompted us to review 25 cases of primary liver cell carcinoma, autopsied in the last 6 years at the Veterans Administra-tion Hospital, Washington, D. C, to deter-mine how frequently portal vein thrombi occur in this disease. For comparison and in an attempt to determine how frequently portal vein thrombi occur in adult patients presenting with hepatomegaly, 100 cases of cirrhosis and 100 cases of carcinoma meta-static to the liver were also reviewed. In addition, we aimed to determine if spleno-
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R Albacete (1967) studied this question.
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