Key result
A high modified frailty index (≥ 0.27) independently predicted a significantly higher risk of postoperative pneumonia (HR 4.427) in patients undergoing curative esophagectomy for esophageal cancer.
Why the study?
Esophagectomy is an invasive, complication-prone procedure, prompting investigation into whether the modified frailty index (mFI) could predict postoperative complications to assist perioperative management.
Does a high modified frailty index predict pneumonia occurrence in patients undergoing curative esophagectomy for esophageal squamous cell carcinoma?
Cohort (n=162)
No
Does a high modified frailty index predict pneumonia occurrence in patients undergoing curative esophagectomy for esophageal squamous cell carcinoma?
Hazard Ratio: 4.427 (95% CI 1.122–17.474)
Absolute Event Rate: 54.5% vs 23.8%
p-value: p=0.034
The modified frailty index may be a useful tool for predicting postoperative pneumonia in patients undergoing esophagectomy.
mFI may aid preoperative risk stratification for post-esophagectomy pneumonia; hypothesis-generating and should not yet change practice.
Background: Esophagectomy is an invasive and complication-prone surgical procedure. Therefore, a tool that can predict the occurrence of postoperative complications may be useful for perioperative management. In this study, we investigated whether the modified frailty index (mFI) could be a useful tool for predicting the postoperative complications of esophagectomy. Methods: In this study, 162 patients who underwent curative esophagectomy for esophageal squamous cell carcinoma from 2004 to 2019 at our institution were included. The patients were divided into the high mFI (≥ 0.27) and low mFI (< 0.27) groups, and the short-term postoperative outcomes of each group were examined retrospectively. Results: = 0.006). Conclusion: The mFI is useful for predicting pneumonia after esophagectomy.
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Miyauchi et al. (2023) conducted a cohort in Esophageal squamous cell carcinoma (n=162). High modified frailty index (≥ 0.27) vs. Low modified frailty index (< 0.27) was evaluated on Postoperative pneumonia (HR 4.427, 95% CI 1.122-17.474, p=0.034). A high modified frailty index (≥ 0.27) independently predicted a significantly higher risk of postoperative pneumonia (HR 4.427) in patients undergoing curative esophagectomy for esophageal cancer.
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