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This topical review outlines state-of-the-art clinical and MRI findings of radiologically isolated syndrome, discusses controversial issues, and highlights potential strategies for future research.
This topical review summarizes the evolving clinical and MRI findings, research obstacles, and future strategies for radiologically isolated syndrome.
RIS review highlights diagnostic obstacles and controversies; leaves open evidence-based management strategies pending prospective trials.
Our understanding of radiologically isolated syndrome (RIS) is evolving, as new data emerge on the clinical characterization and the pathophysiological nature of this rare entity. This topical review aims to (1) outline state-of-the-art clinical and magnetic resonance imaging findings of RIS research; (2) raise the main obstacles to RIS research; (3) discuss the most controversial issues of current RIS findings; and (4) highlight potential strategies for upcoming research studies.
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Labiano-Fontcuberta et al. (2016) conducted a review in Radiologically isolated syndrome (RIS). This topical review outlines state-of-the-art clinical and MRI findings of radiologically isolated syndrome, discusses controversial issues, and highlights potential strategies for future research.
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