Key result
Large thrombus in STEMI patients is an independent predictor of unfavorable PCI results, including <3 TIMI flow (OR 2.87; 95% CI 1.04-8.00; P=0.043).
Why the study?
Does large angiographic thrombus burden predict worse percutaneous intervention outcomes in patients with STEMI?
Population
98 patients with ST-segment-elevation myocardial infarction and TIMI flow grades 0-2 in the infarct-related…
Comparison
Large thrombus vs Small thrombus
Design
Cohort
Authors
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Large thrombus burden signals higher STEMI PCI risk; leaves open whether targeted strategies improve reperfusion.
Observational (n=98)
Does large angiographic thrombus burden predict worse percutaneous intervention outcomes in patients with STEMI?
Odds Ratio: 2.87 (95% CI 1.04–8)
p-value: p=0.043
In STEMI patients, large angiographic thrombus burden is present in about one-third of cases and is strongly associated with worse reperfusion outcomes post-PCI.
Miranda‐Guardiola et al. (2009) conducted an observational in ST-segment-elevation myocardial infarction (STEMI) (n=98). Large thrombus (LT) vs. Small thrombus (ST) was evaluated on <3 TIMI flow (OR 2.87, 95% CI 1.04-8.00, p=0.043). Large thrombus in STEMI patients is an independent predictor of unfavorable PCI results, including <3 TIMI flow (OR 2.87; 95% CI 1.04-8.00; P=0.043).