Key result
Goal-directed fluid therapy significantly decreased total fluid administered compared to conventional therapy (2750 vs 3550, P=0.005), with no differences in postoperative complications.
Why the study?
Optimum perioperative fluid therapy is important to improve surgical outcomes, requiring accurate volume status assessment to achieve hemodynamic stability and adequate tissue oxygenation.
Does goal-directed fluid therapy reduce fluid requirements and improve outcomes compared to conventional fluid therapy in patients undergoing elective colorectal surgery?
RCT (n=100)
Does goal-directed fluid therapy reduce fluid requirements and improve outcomes compared to conventional fluid therapy in patients undergoing elective colorectal surgery?
Goal-directed fluid therapy using noninvasive electrical cardiometry reduces total intraoperative fluid volume without altering organ perfusion or postoperative complications in elective colorectal surgery.
Answers are grounded in this paper and cite their sources.
Electrical cardiometry-guided GDFT may aid volume assessment; leaves open superiority over conventional therapy for lactate and creatinine.
Background: Optimum perioperative fluid therapy is important to improve the outcome of surgical patients, so the assessment of a patient’s volume status accurately is an important goal for the anesthesiologist to achieve hemodynamic stability and adequate tissue oxygenation. Objective: This study compared intraoperative goal-directed fluid therapy (GDFT) versus conventional fluid therapy (CVFT) using noninvasive electrical cardiometry with measuring serum lactate, serum creatinine levels, stroke volume optimization, and postoperative complication. Methods: One hundred patients ASA I -II, both sexes, aged 21-65 years scheduled for elective colorectal surgery were randomized into 2 groups (50 subjects each). GDFT group used Stroke volume optimization, and CVFT used the conventional method of fluid administration. Hemodynamic variables, amount of fluid given, serum lactate, serum creatinine, and postoperative complication were noted. Results: Serum lactate levels were insignificant intra& postoperative except at 6 hrs. postoperative was higher in GDFT 1,79±0.21 than CVFT 1.68±0.23with p value=0.02 but still within normal limits. CVFT received significantly more crystalloids 2750(1500-4000) than GDFT 2250 (1000-3350) with p value=0.002, whereas GDFT received more colloids 350(200-1000) than CVFT 250(0-1000) with p value=0.024. Total fluid received were higher in CVFT 3550(2000-5600) than GDFT 2750(1500-5000) with p-value=0.005. Conclusions: GDFT results in a decreased total volume of crystalloids and fluid given to patients. However, both groups didn’t alter organ perfusion inspite of serum lactate being higher in GDFT and with no differences in postoperative complications in both groups.
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Abdelrahman et al. (2022) conducted an RCT in Elective colorectal surgery (n=100). Goal-directed fluid therapy (GDFT) vs. Conventional fluid therapy (CVFT) was evaluated on Total fluid received (p=0.005). Goal-directed fluid therapy significantly decreased total fluid administered compared to conventional therapy (2750 vs 3550, P=0.005), with no differences in postoperative complications.
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