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An efficient and novel multicomponent reaction for synthesis of new isoxazolinedione has been described. This protocol involves reaction of two molecules of isocyanide, aliphatic oxime, alkylidene substituted Meldrum's acid, and water (moisture). Elemental analyses, IR, 1H NMR, and 13C NMR spectroscopic data of products are consistent with the structure defined by X-ray diffraction analysis.
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Habibi et al. (2013) studied this question.
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