Key result
A high SYNTAX Score (>33 points) was not associated with an increased risk of overall adverse cardiac events at 1 year compared to a low/intermediate score in patients undergoing rotational atherectomy.
Why the study?
The study was conducted to evaluate whether SYNTAX Score results are associated with in-hospital and 1-year outcomes in patients undergoing PCI requiring rotational atherectomy.
Does a high SYNTAX Score predict in-hospital and 1-year adverse cardiovascular events in patients undergoing PCI with rotational atherectomy?
Observational (n=207)
No
Does a high SYNTAX Score predict in-hospital and 1-year adverse cardiovascular events in patients undergoing PCI with rotational atherectomy?
Hazard Ratio: 1.03 (95% CI 0.6–1.5)
p-value: p=0.12
The SYNTAX Score does not significantly predict 1-year adverse cardiovascular events in patients undergoing rotational atherectomy, highlighting the need for a specific risk score in this complex population.
Introduction The SYNTAX Score (SS) evaluates the angiographic complexity of coronary artery disease to assess the cardiovascular risk after coronary revascularization. The aim of the study was to evaluate whether SS results are associated with in-hospital and 1-year outcomes of patients undergoing percutaneous coronary intervention (PCI) requiring rotational atherectomy (RA). Material and methods We analyzed data of 207 consecutive patients who underwent PCI with RA. Patients were divided into two groups: those with high SS (> 33 points) and those with low/intermediate SS (0–33 points). Results In 21 (10%) patients SS was high and 186 (90%) patients had low/intermediate SS. Patients with high SS were older (76 vs. 71 years, p = 0.008) and more frequently diagnosed with chronic kidney disease (38% vs. 18%, p = 0.03) and heart failure (71% vs. 30%, p = 0.0001). In patients with high SS the RA procedure was longer (p = 0.004), required more contrast (p = 0.005) and higher radiation doses (p = 0.04), and contrast-induced nephropathy was more frequent (14% vs. 2%, p = 0.001). Conclusions In our RA patients there was no significant difference between the frequency of in-hospital and 1-year adverse cardiovascular events depending on the SS result. High SS correlates only with parameters describing the extensity and technical complexity of the procedure. However, the unavailability of other risk assessment tools in this population raises the need to create a new more specific risk score for patients requiring RA.
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Brzozowski et al. (2020) conducted an observational in Coronary artery disease requiring percutaneous coronary intervention with rotational atherectomy (n=207). High SYNTAX Score (> 33 points) vs. Low/intermediate SYNTAX Score (0-33 points) was evaluated on Overall adverse cardiac events (HR 1.03, 95% CI 0.60-1.50, p=0.12). A high SYNTAX Score (>33 points) was not associated with an increased risk of overall adverse cardiac events at 1 year compared to a low/intermediate score in patients undergoing rotational atherectomy.
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