Key result
PCI using a drug-coated balloon after rotational atherectomy in calcified de novo coronary lesions resulted in a MACE rate of 14% at 12 months and 20% at 24 months.
Why the study?
Does percutaneous coronary intervention using a drug-coated balloon after rotational atherectomy provide safe and effective outcomes in patients with calcified de novo coronary lesions?
Cohort (n=65)
No
Does percutaneous coronary intervention using a drug-coated balloon after rotational atherectomy provide safe and effective outcomes in patients with calcified de novo coronary lesions?
PCI using a drug-coated balloon after rotational atherectomy is a feasible and effective strategy for calcified de novo lesions, allowing for a short 1-month dual antiplatelet therapy duration that is advantageous for patients at high bleeding risk.
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May support short DAPT with DCB after rotablation in high-bleeding-risk patients; leaves open randomized confirmation of efficacy.
Rissanen et al. (2017) conducted a cohort in calcified de novo coronary lesions (n=65). PCI using drug-coated balloon after rotational atherectomy was evaluated on MACE (composite of cardiovascular death, ischemia-driven target-lesion revascularization, or non-fatal myocardial infarction) at 12 months. PCI using a drug-coated balloon after rotational atherectomy in calcified de novo coronary lesions resulted in a MACE rate of 14% at 12 months and 20% at 24 months.
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