Key result
The addition of ribavirin to interferon therapy significantly improves long-term virological response in patients with chronic hepatitis C compared to interferon alone.
Why the study?
Does the addition of ribavirin to interferon therapy improve sustained virological response in patients with chronic hepatitis C?
Does the addition of ribavirin to interferon therapy improve sustained virological response in patients with chronic hepatitis C?
Combination therapy with ribavirin and interferon improves virological response in chronic hepatitis C but is associated with increased adverse effects like hemolytic anemia.
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May improve response in hepatitis C; leaves open benefit-risk balance and relevance versus modern antivirals.
Thierry Poynard (2004) conducted a review in Chronic hepatitis C. Interferon alfa and ribavirin combination therapy vs. Interferon alfa alone was evaluated. The addition of ribavirin to interferon therapy significantly improves long-term virological response in patients with chronic hepatitis C compared to interferon alone.
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