An Expedient Method to the Synthesis of N-Substituted 1H-Isoindole-1,3(2H)-diones

The synthesis of N-substituted 1H-isoindole-1,3-(2H)-diones is described from the reaction of cyclic anhydrides with Schiff bases as suitable replacing substrates instead of the corresponding amines.Imines with an aryl or a benzyl group on nitrogen (Schiff bases), are stable to oxygen and water.They are readily prepared and are promising starting materials in biologically important systems and hence attract